Follow these best practices for error handling in Node.js:

• Use Try-Catch: Wrap synchronous code in try-catch blocks.
• Promise and Async/Await Errors: Use .catch() for promises and try-catch for async/await.
• Global Error Handling: Use an error-handling middleware for Express apps.
• Process-Level Errors: Handle uncaughtException and unhandledRejection.
• Logging: Use tools like Winston or Bunyan for structured error logging.

Example for Express:

app.use((err, req, res, next) => {
 console.error(err.stack);
 res.status(500).json({ message: 'Something went wrong!' });
});